INDUCTION OF DOMINANT LETHAL MUTATIONS IN DROSOPHILA
MELANOGASTER UNDER THE COMPLEX INFLUENCE
OF IRRADIATION AND SOME CHEMICAL REAGENTS
N. Kimak, Ya. Chernyk
Ivan Franko National University of Lviv
Hrushevskyi St. 4, UA-79005 Lviv, Ukraine
The frequency of dominant lethal mutations (DLM) appearance in Drosophila induced both by irradiation and the by complex effect of irradiation with nitrosoethylurea and with coffeine has been analyzed. It has been shown that the frequencies of DLM by the influence of irradiation in total doses 1000 and 3000R had no differences between themselves but the dose increasing led mainly tî embryonic death at the early stages of the egg development. The complex effect of irradiation and chemical agents induced the highest frequency of DLM appearance. The index of early embryonic death appearance was several times higher in comparison to the index of the late embryonic death.
Key words: Drosophila melanogaster, dominant lethal mutations, frequency of embryonic death.
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